刘河生,现任昌平实验室首席科学家,北京大学生物医学前沿创新中心教授。曾历任哈佛大学附属麻省总医院 Martinos中心人脑个体差异实验室主任,美国南卡罗莱纳医科大学终身正教授,SmartState讲席教授,南卡罗莱纳医科大学脑影像计算中心主任、生物医学成像中心副主任等职。过去十年,刘教授培养博士,博士后共五十余人,多人在哈佛大学,慕尼黑大学等世界名校取得教职。刘教授长期从事脑功能成像研究,是国际上把功能核磁推向临床应用的最主要贡献者之一。他开发的个体脑功能图谱技术被认为是神经影像的一个转折点。刘教授在Nature Neuroscience, Neuron, PNAS等神经科学期刊发表100多篇论文,总引用次数20000余次。他主持的多项美国 NIH 科研项目总研究经费超过2000万美元, 他作为子课题负责人参与美国国立卫生署5个重大项目,项目总经费超过一亿美元。刘教授是 Brain Informatics 共同主编, Frontiers in Psychiatry 副主编,并任多个学术期刊的编委。
个人履历
2021-现在 昌平实验室,首席科学家
2021-现在 北京大学,北京大学生物医学前沿创新中心,教授
2019-2021 美国南卡罗莱纳医科大学,神经科学系,Smart State讲席教授
2019-2021 美国南卡罗莱纳医科大学,神经影像计算中心,主任
2012-2019 美国哈佛大学附属麻省总医院,脑个体差异实验室,主任
2016-2019 美国哈佛大学医学院,放射学系,副教授
2012-2016 美国哈佛大学医学院,放射学系,助理教授
2009-2012 美国哈佛大学医学院,放射学系,讲师
2006-2009 美国哈佛大学附属麻省总医院,放射学系,博士后
2004-2006 美国华盛顿州立大学,计算机科学,博士后
2003, 清华大学,工学博士
1997, 清华大学,工学学士
获奖及荣誉
2023年 政府特殊津贴
2021年 科技部创新人才
2021年 北京市战略科技人才
2021年 美国国际创伤后应激障碍学会 Pierre Janet 最佳论文奖
2019 年 美国南卡罗来纳州 Smart State Endowed Chair
2013年 脑与行为研究基金会 (NARSAD)青年研究员奖
代表性论文
(刘河生教授为第一作者或通信作者)
Google 学术:https://scholar.google.com/citations?hl=zh-CN&user=86URon8AAAAJ
1. Peng X, Liu Q, Hubbard C, Wang D, Zhu W, Fox MD, Liu H., Robust dynamic brain coactivation states estimated in individuals, Science Advances, 2022
2. Trambaiolli, L. R., Peng, X., Lehman, J. F., Linn, G., Russ, B. E., Schroeder, C. E., Liu, H. #, Haber, S. N. #, “Anatomical and functional connectivity support the existence of a salience network node within the caudal ventrolateral prefrontal cortex”,Elife, 11, 2022.
3. Cui W, Wang Y, Ren J, Hubbard CS, Fu X,Fang S, Wang D, Zhang H, Li Y, Li L, Jiang T., Liu H. “Personalized fMRI delineates functional regions preserved within brain tumors” . Annals of neurology, 2021.
4. Wang D., Peng X., Pelletier-Baldelli A., Orlov N., Farabaugh A., Nasr S., Eryilmaz H., Fava M., Holmes A., Roffman J.L., Liu H. #, Holt D. #, “Altered temporal, but intact spatial, features of transient network dynamics in psychosis”, Molecular Psychiatry, 2021
5. Yan Y., Dahmani L., Ren J., Shen L., Peng X., Wang R., He C., Jiang C., Gong C., Tian Y., Zhang J., Guo Y., Lin Y., Li S., Wang M., Li L., Hong B., Liu H., "Reconstructing lost BOLD signal in individual participants using deep machine learning", Nature Communications, 2020
6. Stoecklein S., Hilgendorff A., Li M., Förster K., Flemmer A.W., Galiè F., Wunderlich S., Wang D., Stein S., Ehrhardt H., Dietrich O., Zou Q., Zhou S., Ertl-Wagner B., Liu H. “Variable Functional Connectivity Architecture of the Preterm Human Brain: Impact of Developmental Cortical Expansion and Maturation” Proc Natl Acad Sci USA, 2020
7. Lebois L., LiM., Baker J.T., Wolff J., Wang D., Grinspoon E., Winternitz S., Ren J., Ressler K., Liu H. #, Kaufman M. #, “Large-scale functional brain network architecture changes associated with trauma-related dissociation”, Am. J. Psychiatry, 2020
8. Shen L., Jiang C., Hubbard C.S., Ren J., He C., Wang D., Dahmani L., Guo Y., Liu Y., Xu S., Meng F., Zhang J., Liu H.# , Li L. # “Subthalamic nucleus deep brain stimulation modulates two distinct neurocircuits”, Annals of Neurology, 2020
9. Stoecklein,V.M., Stoecklein, S., Galiè, F., Ren, J., Schmutzer, M., Unterrainer, M., Albert, N.L., Kreth, F.W., Thon, N., Liebig, T. and Ertl-Wagner, B., Tonn J.C., Liu H. “Resting-state fMRI Detects Alterations in Whole Brain Connectivity Related to Tumor Biology in Glioma Patients.” Neuro-Oncology. 2020
10. Liu H., Xiaolong Peng X., Dahmani L., Wang H. , Zhang M., Shan Y., Rong D., Guo Y., Li J., Li N., Wang L., Lin Y., Pan R. Lu J., Wang D., “Different stroke-induced striatal lesions lead to differential structural brain reorganization” Neurology, 2020
11. Wang D., Li M., Wang M., Schoppe F., Ren J., Chen H., Ongur D., Baker J.T., Liu H., “Individual-specific functional connectivity markers track dimensional and categorical features of psychotic illness”, Molecular Psychiatry, 2020
12. Li M., Wang D., Ren J., Langs G., Stoecklein S., Brennan B.P., Lu J., Chen H., Liu H., “Performing group-level functional image analyses based on homologous functional regions mapped in individuals”, PLoS Biology, 2019
13. Tang W.#, Liu H.#, Douw L., Kramer M.A., Eden U.T., Hämäläinen M.S., Stufflebeam S.M., Dynamic connectivity modulates local activity in the core regions of the default- mode”, Proc Natl Acad Sci USA ， 2017
14. Wang D, Buckner RL, Fox MD, Holt DJ, Holmes AJ, Mueller S, Langs G, Pan R, Qian T, Li K, Baker J, Stufflebeam SM, Wang K, Wang X, Hong B, Liu H. “Parcellating Cortical Functional Networks in Individuals” . Nature Neuroscience, 2015
15. Mueller S., Wang D., Pan R., Holt D., Liu H., “Abnormalities in hemispheric specialization of caudate nucleus connectivity in schizophrenia”, JAMA Psychiatry, 2015
16. Zeng L., Wang D., Fox M.D., Sabuncu M., Hu D., Ge M., Buckner R.L., Liu H., “Neurobiological basis of head motion in brain imaging” . Proc Natl Acad Sci USA, 2014
17. Mueller S., Wang D., Fox M.D., Yeo B.T.T., Sepulcre J., Sabuncu M.R., Shafee R., Lu J., Liu H., “Individual variability in functional connectivity architecture of the human brain”, Neuron, 2013
18. Liu H., Stufflebeam S.M., Sepulcre J., Hedden T., Buckner R.L., “Evidence from Intrinsic Activity that Asymmetry of the Human Brain is Controlled by Multiple Factors”, Proc Natl Acad Sci USA, 2009.
19. Liu. H., Agam Y., Madsen J.R., Kreiman G., “Timing, timing, timing: fast decoding of object information from intracranial field potentials in human visual cortex”,Neuron, 2009.
